Effect On The Body
THC is the psychoactive component of cannabis, and it binds to these two receptors: CB-1 and CB-2. CB-1 influences pleasure, appetite, memory, and concentration, while CB-2 moderates the sensation of pain, and plays a role in homeostasis in certain parts of the body, such as the kidney and liver. THC increases the appetite, in addition to causing drowsiness. That is why it is mostly used in treatments against insomnia and loss of appetite. THC is the most popular among smokers but is banned in most countries.
CBD, for its part, interacts with receptors such as GPR55 or 5-HT1A. It has anti-inflammatory properties that far exceed THC, and without psychotropic effects, making it safe for any patient. It is widely used in diseases such as arthritis and rheumatism. While THC is used for recreational purposes, CBD is used for medical use. CBD, like THC, interacts with the CB-1 receptor, but differently. It does not activate it but complicates its activation by other substances. This prevents THC from binding to the CB-1 receptor. Therefore, the presence of CBD has a significant effect on THC-containing psychoactivity.
Nevertheless, the WHO (World Health Organization) confirmed the possibility of CBD abuse and suggested its negative impact on human health. Therefore, the phrase "no side effects have been confirmed" does not guarantee that it is completely safe.
Both THC and CBD have confirmed side effects. However, there are major differences in their symptoms and seriousness.
THC is considered an addictive substance with mostly negative effects on the body and mind. THC can cause a feeling of uplifting when taken, but it is also known that the reaction causes bad symptoms:
THC acts strongly on the pathway of the reward system in the brain. Simply put, the brain responds to a stimulus and then seeks to repeat it. Dependencies on THC have also been confirmed. Although there is a hypothesis that the dependence on THC is minimal (as dependence on caffeine), the cessation of THC in some cases leads to a negative reaction of the body. Therefore, it is important to remember the side effects and quality of cannabis.
2. Continuous intake of THC affects mental and brain function.
The unofficial name of the effects of cannabis is psychosis. The main symptoms are hallucinations, mood swings, memory loss, and decreased ability to solve problems. Such symptoms are thought to be similar to the symptoms of schizophrenia. It is also observed such effects on the body like increased heart rate, impaired motor function, nausea, and vomiting. In 2016, a study at Osaka University discovered that cannabis cuts off the necessary networks of the cranial nerves, showing that cannabis has a serious adverse effect on brain function.
CBD also has some side effects including dizziness, nausea, diarrhea, and loss of appetite due to high dose intake. However, unlike THC, it does not cause serious damage to mental and brain functions, and it is said that it has a little adverse effect on the mind and body.
Nevertheless, the listed side effects concern the majority of users, but there are various reactions of an organism depending on the features of each person.