Eremophila glabra grows to 0.1–3 m (0.3–10 ft) in height, sometimes a prostrate shrub and sometimes erect. The leaves are arranged alternately, sometimes crowded, other times sparse, usually lance-shaped but they may also be linear to egg-shaped. They are 7.5–61 mm (0.3–2 in) long and 0.8–18 mm (0.03–0.7 in) wide, the end pointed and the base tapering gradually towards the stem.
Dieffenbachia and Euphorbia spp. are irritating to skin and dermatitis can develop in people who handle these plants frequently.